On her first visit to the capital after assuming office, Jayalalithaa will meet Prime Minister Manmohan Singh and is expected to discuss issues like Sri Lankan Tamils and various developmental projects in her state.
The visit comes at a time when there are growing strains in the seven-year-old alliance between Congress and DMK after the drubbing in Tamil Nadu and Puducherry elections for which Congress has blamed the 2G scam.
Congress chief Sonia Gandhi had congratulated Jayalalithaa over phone after her victory, a gesture which set off speculation that the two parties would come together after more than a decade.
The DMK is the third largest constituent of the United Progressive Alliance (UPA) after the Congress and the Trinamool Congress. It has 18 members in Lok Sabha. The party has six ministers in the Union Council (Cabinet).
The DMK lost heavily the elections in Tamil Nadu this year. J Jayalalithaa in Tamil Nadu returned to power as her party All India Anna Dravida Munnetra Kazhagam (AIADMK) bagged 203 seats against 31 by DMK in state assembly polls conducted in April-May.